FIRST RESPONSE® - Ovulation Test

FIRST RESPONSE® OVULATION TEST

Instructions and Use
How the First Response® Ovulation Test Works
Limitations of the Test
When to Begin Testing
How to Perform the Test
How to Read the Test Results
Questions and Answers

PLEASE READ ALL THE INFORMATION IN THIS
LEAFLET BEFORE PERFORMING THE TEST. THE
DIRECTIONS SHOULD BE FOLLOWED PRECISELY
TO GET ACCURATE RESULTS.

Do not use this product after expiration date stamped on the side of the carton.
Store in a dry place below 86°F (30°C).
Do not freeze.
Keep out of reach of children.
For In Vitro diagnostic use. Not to be taken internally.
This test cannot be used for contraception (birth control) or gender selection.
This test is not reusable.
If you have any questions, call us toll-free at 1-800-367-6022, Monday-Friday, 7:00AM-5:00PM, Eastern Time.
Visit us online at www.tellsyoufirst.com.

Luteinizing hormone (LH) is always present in your urine and increases just before ovulation. This increase or "surge" in LH triggers ovulation, which is the release of an egg from your ovary. This is also the most fertile time of your cycle.

The FIRST RESPONSE® Ovulation Test detects the LH surge which precedes ovulation by 24-36 hours. Your two most fertile days begin with the LH surge. If you have intercourse within the next 24-36 hours, you will maximize your chances of becoming pregnant.

Some prescription drugs, such as menotropins for injection (e.g., Pergonal1) and danazol (e.g., Danocrine2), may affect the result you see with the FIRST RESPONSE® Ovulation Test. If you are undergoing therapy with Clomiphene citrate (e.g., Clomid3 or Serophene4), please consult your physician about how this may affect your test result.

Medications containing hCG or LH may affect the test and should not be taken while using this test. In addition, the results of the test may not be valid if you are taking oral contraceptives. Some women do not ovulate every cycle and they will not see any increase in the level of LH during these non-ovulating cycles. Certain medical conditions may adversely affect the reliability of this test for predicting ovulation. These include pregnancy, postpartum, post-abortion, polycystic ovary syndrome (PCOS), ovarian cysts, the onset of menopause, and untreated hypothyroidism. Women with medically diagnosed fertility problems should consult their physicians before using this product.

FIRST RESPONSE is a registered trademark of Church & Dwight Co., Inc.

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You may test at any time of day, but you should test approximately the same time each day. Reduce your liquid intake for 2 hours before testing.

To find out when to begin testing, determine the length of your normal cycle. The length of your cycle is from the beginning of one period to the beginning of the next. Count the first day of bleeding or spotting as day 1.

If your cycle length is irregular, that is, if it varies by more than a few days each month, take the average number of days for the last 3 months. Use the chart below to figure out the day you should begin testing. The day you begin testing is listed opposite the number of days in your cycle.

Example: Ms. Smith has a regular cycle of 28 days, and is starting her period on the 4th. Beginning with the 4th as day 1, she counts forward 11 days and begins testing on the 14th.

Note: If you are unsure about your cycle length or when to start testing, call our consumer information staff toll-free at
1-800-367-6022, Monday-Friday, 7:00AM-5:00PM, Eastern Time.

Menstrual cycles can be irregular. If 7 days of testing does not detect your hormone surge, you may continue testing with a second FIRST RESPONSE® Ovulation Test. Once you think you may be pregnant, you can test this as early as 4 days before you expect your period by using the FIRST RESPONSE® Early-Result Pregnancy Test.

Remove the test stick from the foil wrapper and take off the Overcap.
Holding the test stick by the Thumb Grip with the Absorbent Tip pointing downward and the Result Window facing away from your body, place the Absorbent Tip in your urine stream for 5 seconds only. (You may also collect your urine in a clean, dry cup and immerse the entire Absorbent Tip in the urine for 5 seconds).
With the Absorbent Tip still pointing downward, replace the Overcap* and lay the test stick on a flat surface with the Result Window facing up.
Read your result according to the instructions that follow.

*Replacement of the Overcap is not necessary for proper functioning of the test.

You may soon see a pink color moving across the Result Window to indicate that the test is working. Look at the Result Window at 5 minutes. Compare the test line to the reference line. The reference line indicates that the test is complete, and you have conducted it correctly.
Here are examples of the results you can expect to see (however, they may not look exactly as shown):


LH SURGE LH Surge. Two lines are visible and the color and intensity of the Test Line is similar to or darker than the Reference Line. You should ovulate within the next 24-36 hours. You can stop testing for this cycle.	NO LH SURGE No LH Surge. Two lines are visible but the Test Line is lighter than the Reference Line or there is a Reference Line and NO visible Test Line. You should continue with daily testing until the Reference Line and the Test Line have the same color intensity or the Test Line is darker than the Reference Line.

After you have read your result, the test should be discarded. The result can be read up to 1 hour. Once you know you are about to ovulate, you are at the start of the most fertile time of your monthly cycle. If you have intercourse within 24-36 hours after you detect your LH surge, you will maximize your chances of becoming pregnant. There is no need to wait until you ovulate before having intercourse.

If you have any questions about interpreting your test results, you can call a member of our consumer information staff at our toll-free number 1-800-367-6022, Monday-Friday, 7:00AM-5:00PM, Eastern Time.

Once you think you may be pregnant, you can test this with the FIRST RESPONSEŽ Early Result Pregnancy Test, as early as 4 days before you expect your period.

Q: When can I do the test?
A: After you determine the best day to start testing based on your monthly cycle, you can do the FIRST RESPONSE® Ovulation Test any time that day. You do not have to use your first morning urine. However, you should do the test about the same time each day. Reduce your liquid intake for 2 hours before testing, since drinking excessive amounts of liquid can dilute the LH in your urine.

Q: How accurate is the FIRST RESPONSE® Ovulation Test?
A: The FIRST RESPONSE® Ovulation Test is over 99% accurate in detecting the LH surge in laboratory studies.

Q: I have used all 7 tests and I do not see a surge. What do I do?
A: Since not every woman ovulates mid-cycle, you may not detect the LH surge in the first 7 days of testing. This could mean you have not ovulated yet and you should continue testing with additional FIRST RESPONSE® Ovulation Tests.

Q: I have used the FIRST RESPONSE® Ovulation Test for three months, and have not become pregnant yet. What is wrong?
A: First, it is important to remember that it can take normal, healthy couples many months to become pregnant. There are many factors which affect your ability to become pregnant even if you have been able to have intercourse during your most fertile time. If after several months you have no success, consult your physician. Since you have been monitoring your LH surge with the FIRST RESPONSE® Ovulation Test, you will be able to give your doctor a clearer picture of how you have been ovulating.

Q: Once I detect my LH surge, when is the best time to have intercourse?
A: Your two most fertile days begin with the LH surge. You are most likely to get pregnant if you have intercourse within 24-36 hours after you detect your LH surge.

Q: I have waited longer than five minutes, and still there are no lines in the Result Window. Is there anything wrong?
A: There should be at least one pink line in the Result Window at five minutes. If not, the test is invalid. This could be due to insufficient urine on the Absorbent Tip or not holding the stick with the Tip pointing downward while replacing the Overcap. You should retest with another stick, carefully following all directions.

Q: Will my result change if left standing for a certain period of time?
A: The result can be read up to 1 hour.

Q: Do any medical conditions or drugs affect the test?
A: Certain medical conditions may adversely affect the reliability of this test for predicting ovulation. These include pregnancy, postpartum, post-abortion, polycystic ovary syndrome (PCOS), ovarian cysts, the onset of menopause, and untreated hypothyroidism. Some prescription drugs, such as menotropins for injection (Pergonal) and danzol (Danocrine), may affect the result you see. If you are undergoing therapy with Clomiphene citrate (e.g., Clomid or Serophene), please consult your physician for the appropriate time to begin testing. Medications containing hCG or LH may affect the test and should not be taking while using this test. Women with medically diagnosed fertility problems should consult their physician before using this product.

Q: Will oral contraceptives affect the results?
A: After using the pill your cycle may be irregular and make take some time to stabilize again. You may wish to wait until you have had two normal periods before starting to use the FIRST RESPONSE® Ovulation Test. Follow your physician's advise on when to best try to become pregnant.

Q: If the FIRST RESPONSE® Ovulation Test can determine my most fertile time, why can't I use it for contraception (birth control)?
A: Sperm can survive up to 72 hours (3 days), and this test predicts your LH surge only up to 24-36 hours in advance. Therefore, if you have intercourse before you discover your surge, the egg can still be fertilized.

To increase your chances for a healthy pregnancy for you and your baby, you should consider the following:

Maintain a well-balanced diet.
Stop Smoking.

From conception through the first three months of pregnancy is the most important time. You need to see your doctor immediately for proper care and nutrition counseling.

WARNING: According to the Surgeon General, women should not drink alcoholic beverages during pregnancy because of the risk of birth defects.